Description

Benzenesulfonic Acid, 4-Methoxy-, 2-(1,1-Dioxido-1,2-Benzi CAS NO 351066-12-1 is a specialized sulfonated aromatic compound featuring a methoxy substituent and a benzisothiazole dioxide moiety. This unique molecular structure makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers requiring precise, reliable building blocks for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring sulfonamide-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, where the sulfonic acid group contributes to biological activity and solubility.
• Dye and Pigment Manufacturing: Serves as a precursor or functionalizing agent for creating specialized sulfonated dyes with enhanced color fastness and water solubility.
• Polymer Modification: Employed to introduce sulfonic acid groups into polymer chains, imparting properties like ion-exchange capacity or improved hydrophilicity for membrane and resin applications.
• Organic Synthesis Reagent: Acts as a catalyst or a reactant in various organic transformations, including Friedel-Crafts alkylation and sulfonation reactions.
• Research & Development: Utilized in academic and industrial laboratories for methodological studies and the development of new synthetic pathways involving complex sulfonated aromatics.

Basic Information

Item	Details
Product Name	Benzenesulfonic Acid, 4-Methoxy-, 2-(1,1-Dioxido-1,2-Benzi CAS NO 351066-12-1
CAS No.	351066-12-1
Molecular Formula	C14H11NO5S2
Molecular Weight	337.37 g/mol
Synonyms	4-Methoxy-2-(1,1-dioxido-1,2-benzisothiazol-3-yl)benzenesulfonic acid; 2-(1,1-Dioxido-1,2-benzisothiazol-3-yl)-4-methoxybenzenesulfonic acid; 3-(5-Methoxy-2-sulfophenyl)-1,2-benzisothiazole 1,1-dioxide; Benzenesulfonic acid, 4-methoxy-2-(1,1-dioxido-1,2-benzisothiazol-3-yl)-; 351066-12-1; 4-Methoxy-2-(1,2-benzisothiazol-3-yl-1,1-dioxide)benzenesulfonic acid
EINECS	Contact for details

Quality Control

Our production of Benzenesulfonic Acid, 4-Methoxy-, 2-(1,1-Dioxido-1,2-Benzi CAS NO 351066-12-1 adheres to a rigorous quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for use in sensitive applications like pharmaceutical synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and compliance assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.