Description

3,4,5-Trifluorobenzenesulfonyl Chloride is a high-value fluorinated aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in introducing the reactive sulfonyl chloride group into a highly fluorinated benzene core, enabling the creation of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the production of novel herbicides and fungicides, where the trifluoromethyl and sulfonyl groups enhance biological activity and stability.
• Material Science: Precursor for creating specialty polymers, liquid crystals, and electronic materials that benefit from fluorine's unique properties.
• Chemical Research: A versatile reagent for introducing the 3,4,5-trifluorobenzenesulfonyl moiety into target molecules in medicinal and process chemistry.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	3,4,5-Trifluorobenzenesulfonyl Chloride
CAS No.	351003-43-5
Molecular Formula	C6H2ClF3O2S
Molecular Weight	230.59 g/mol
Synonyms	Benzenesulfonyl chloride, 3,4,5-trifluoro-; 3,4,5-Trifluorophenylsulfonyl chloride; 3,4,5-Trifluorobenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-3,4,5-trifluorobenzene; 3,4,5-Trifluoro-1-sulfonyl chloride benzene
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluorobenzenesulfonyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.