Description

Ethanone, 1-(2-Aminophenyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethylated aromatic ketone building block, identified by CAS NO 351002-89-6. This compound is valued for its unique molecular architecture, combining an electron-withdrawing trifluoroacetyl group with an ortho-amino substituent, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the synthesis of novel heterocycles and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing fused heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance metabolic stability and lipophilicity.
• Material Science Research: Serves as a building block for creating specialty polymers and organic electronic materials due to its unique electronic properties.
• Ligand and Catalyst Development: The ortho-aminophenyl moiety can be utilized to develop novel chelating ligands for catalytic systems.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on introducing fluorine atoms into complex molecules to modulate their physical and chemical properties.

Basic Information

Product Name	Ethanone, 1-(2-Aminophenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	351002-89-6
Molecular Formula	C8H6F3NO
Molecular Weight	189.14 g/mol
Synonyms	2'-Amino-2,2,2-trifluoroacetophenone; 1-(2-Aminophenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-aminophenyl)ethanone; 2-Aminophenyl trifluoromethyl ketone; α,α,α-Trifluoro-2-aminoacetophenone; o-Aminophenyl trifluoromethyl ketone; TFAP (abbreviation); 2-Amino-α,α,α-trifluoroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Aminophenyl)-2,2,2-Trifluoro- (9Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.