Description

S-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3-Carboxaldehyde is a specialized chiral binaphthyl derivative, a crucial advanced intermediate in asymmetric synthesis. This compound matters for its role as a key building block in constructing complex, enantiomerically pure molecules, particularly for pharmaceuticals and advanced materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring high stereochemical purity.
• Chiral Ligand Synthesis: Serves as a foundational scaffold for developing proprietary chiral ligands and catalysts used in asymmetric hydrogenation, cross-coupling, and other enantioselective transformations.
• Agrochemical Research: Used in the research and development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is essential for bioactivity and environmental safety.
• Material Science: Employed in the synthesis of chiral polymers, liquid crystals, and other functional materials with specific optical or electronic properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in organic chemistry and catalysis.

Basic Information

Product Name	S-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3-Carboxaldehyde
CAS No.	349149-07-1
Molecular Formula	C26H24O5
Molecular Weight	416.47 g/mol
Synonyms	(S)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene-3-carboxaldehyde; (S)-3-Formyl-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl; (S)-BINOL MOM-Protected Aldehyde; (S)-2,2'-Di(methoxymethoxy)-1,1'-binaphthyl-3-carbaldehyde; (S)-3-Carbaldehyde-2,2'-bis(methoxymethoxy)-1,1'-binaphthalene; S-BINOL(MOM)2-3-CHO; (S)-BINOL Derivative Aldehyde
EINECS	Contact for details

Quality Control

Our S-2,2'-Bis(Methoxymethoxy)-[1,1'-Binaphthalene]-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.