Description

n-(3,4-Difluorophenyl)-4-Fluorobenzamide, 97% is a high-purity fluorinated benzamide derivative, a key building block in advanced organic synthesis. This compound is valued for its role in the research and development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine substitution pattern is critical for modulating biological activity and physicochemical properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce targeted fluorination into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and synthesis of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, where fluorine atoms enhance stability and bioavailability.
• Material Science Precursor: Used in the development of specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP or non-GMP conditions.

Basic Information

Product Name	n-(3,4-Difluorophenyl)-4-Fluorobenzamide, 97%
CAS No.	349129-89-1
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	4-Fluoro-N-(3,4-difluorophenyl)benzamide; 4-Fluorobenzoic acid (3,4-difluoroanilide); N-(3,4-Difluorophenyl)-4-fluorobenzamide; 349129-89-1; Benzamide, N-(3,4-difluorophenyl)-4-fluoro-; (3,4-Difluorophenyl)(4-fluorobenzoyl)amine
EINECS	Contact for details

Quality Control

Our n-(3,4-Difluorophenyl)-4-Fluorobenzamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.