Description

2-(2-Carbethoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is a specialized organoboron compound, specifically a cyclic boronic ester, valued for its role as a key synthetic intermediate. Its primary importance lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing carbon-carbon bonds in complex molecule synthesis. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and complex molecule construction.
• Ligand and Catalyst Development: Employed in the synthesis of novel boron-containing ligands for catalytic systems.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty and performance chemicals.

Basic Information

Product Name	2-(2-Carbethoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	346656-34-6
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	5,5-Dimethyl-2-[2-(ethoxycarbonyl)phenyl]-1,3,2-dioxaborinane; 2-(2-Ethoxycarbonylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; Ethyl 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate; 2-Carbethoxyphenylboronic acid neopentyl glycol ester; Boronic acid, B-[2-(ethoxycarbonyl)phenyl]-, 2,2-dimethyl-1,3-propanediyl ester
EINECS	Contact for details

Quality Control

Our 2-(2-Carbethoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.