Description

3-Chloro-5-Methanesulfonyl-1H-[1,2,4]Triazole is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a chloro and a methanesulfonyl substituent on the triazole core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients. Its reliable quality and consistent supply are critical for accelerating innovation in drug discovery and crop protection solutions.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for creating molecules with potential biological activity.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Chemical Research: Acts as a versatile building block in academic and industrial laboratories for exploring new heterocyclic chemistry and reaction methodologies.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for catalytic systems due to its functional group array.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of complex target molecules for clients.

Basic Information

Product Name	3-Chloro-5-Methanesulfonyl-1H-[1,2,4]Triazole
CAS No.	346631-06-9
Molecular Formula	C3H4ClN3O2S
Molecular Weight	181.60 g/mol
Synonyms	3-Chloro-5-(methylsulfonyl)-1H-1,2,4-triazole; 5-(Methylsulfonyl)-3-chloro-1H-1,2,4-triazole; 1H-1,2,4-Triazole, 3-chloro-5-(methylsulfonyl)-; 3-Chloro-5-methanesulphonyl-1H-[1,2,4]triazole; 346631-06-9; 3-Chloro-5-methylsulfonyl-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Methanesulfonyl-1H-[1,2,4]Triazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.