Description

6-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydroquinoline is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines a tetrahydroquinoline core with a fluorine substituent and gem-dimethyl groups, enabling precise modulation of physicochemical properties in target molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and oncology research, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the tetrahydroquinoline structure contributes to biological activity.
• Material Science Research: Serves as a precursor for functional dyes, ligands for catalysis, and other specialty chemicals requiring a rigid, fluorinated nitrogen heterocycle.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and tags to study biological systems.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	6-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydroquinoline
CAS No.	345264-92-8
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	6-Fluoro-4,4-dimethyl-1,2,3,4-tetrahydroquinoline; 4,4-Dimethyl-6-fluoro-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6-fluoro-4,4-dimethylquinoline; 6-Fluoro-4,4-dimethyl-3,4-dihydro-2H-quinoline; 345264-92-8; FDTQ
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4,4-Dimethyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.