Description

2,1-Benzisoxazol-3(1H)-One,5-Chloro-(9Ci) is a specialized heterocyclic organic compound that serves as a critical synthetic intermediate and building block in advanced chemical synthesis. Its value lies in its unique fused isoxazolone structure, which provides a versatile scaffold for constructing complex molecules with targeted biological or material properties. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated benzisoxazolone core for bioactivity.
• Material Science Research: Serves as a precursor for creating specialized polymers, ligands, or organic electronic materials due to its rigid, heteroaromatic structure.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes, enzyme inhibitors, or activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry within university and CRO laboratories.

Basic Information

Product Name	2,1-Benzisoxazol-3(1H)-One,5-Chloro-(9Ci)
CAS No.	344779-31-3
Molecular Formula	C7H4ClNO2
Molecular Weight	169.56 g/mol
Synonyms	5-Chloro-1,2-benzisoxazol-3(1H)-one; 5-Chloro-1,2-benzisoxazol-3-ol; 5-Chloro-3-hydroxy-1,2-benzisoxazole; 5-Chlorobenzisoxazol-3-one; 5-Chloro-1,2-benzisoxazol-3-one; 344779-31-3; 5-Chloro-1,2-benzisoxazol-3(1H)-one (9CI)
EINECS	Contact for details

Quality Control

Our 2,1-Benzisoxazol-3(1H)-One,5-Chloro-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profiles. We support customer audits and can provide material to meet the stringent requirements of cGMP environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to strong light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.