Description

2-Chloro-4-Methoxy-3-Pyridinecarboxylic Acid Methyl Ester is a high-purity pyridine derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized pyridine core, which provides a versatile scaffold for constructing complex molecules with tailored biological and chemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or with kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the pyridine moiety is a core structural element.
• Material Science Research: Acts as a precursor for developing functionalized ligands, organic semiconductors, or metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical space.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	2-Chloro-4-Methoxy-3-Pyridinecarboxylic Acid Methyl Ester
CAS No.	344298-51-7
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	Methyl 2-Chloro-4-methoxynicotinate; 2-Chloro-4-methoxypyridine-3-carboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 2-chloro-4-methoxy-, methyl ester; 2-Chloro-4-methoxy-3-pyridinecarboxylate; Methyl 2-chloro-4-methoxypyridine-3-carboxylate; 2-Chloro-4-methoxy-nicotinic acid methyl ester; Nicotinic acid, 2-chloro-4-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxy-3-Pyridinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.