Description

4'-Trifluoromethyl-Biphenyl-3-Carbaldehyde is a high-purity organic building block characterized by its biphenyl core functionalized with both a formyl and a trifluoromethyl group. This compound matters as a versatile and critical intermediate in modern synthetic chemistry, enabling the precise construction of complex molecules for advanced applications. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of advanced electronic materials for displays and lighting due to its rigid biphenyl structure.
• Organic Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: An excellent substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Fine Chemical Production: A versatile starting material for synthesizing dyes, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	4'-Trifluoromethyl-Biphenyl-3-Carbaldehyde
CAS No.	343604-24-0
Molecular Formula	C14H9F3O
Molecular Weight	250.22 g/mol
Synonyms	3-Formyl-4'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-3-carboxaldehyde, 4'-(trifluoromethyl)-; 4'-(Trifluoromethyl)biphenyl-3-carbaldehyde; 3-Formyl-4'-trifluoromethylbiphenyl; 4'-Trifluoromethyl-3-biphenylcarboxaldehyde; Biphenyl-3-carbaldehyde, 4'-trifluoromethyl-
EINECS	Contact for details

Quality Control

Our 4'-Trifluoromethyl-Biphenyl-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.