Description

4-Fluoro-n-(1-Hydroxy-2-Methyl-Propan-2-Yl)Benzamide is a high-purity, specialized organic intermediate featuring a benzamide core with a fluoro substituent and a tertiary alcohol-bearing side chain. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs), fine chemicals, and advanced material precursors. The CAS number for this compound is 343316-37-0.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers or additives for high-performance polymers and specialty coatings.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	4-Fluoro-n-(1-Hydroxy-2-Methyl-Propan-2-Yl)Benzamide
CAS No.	343316-37-0
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	4-Fluoro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide; 4-Fluoro-N-(2-hydroxy-1,1-dimethylethyl)benzamide; 2-Amino-2-methyl-1-propanol, N-(4-fluorobenzoyl)-; N-(4-Fluorobenzoyl)-2-amino-2-methyl-1-propanol; 343316-37-0; 4-Fluoro-N-(2-hydroxy-2-methylpropyl)benzamide (common misnomer); p-Fluoro-N-(1-hydroxy-2-methyl-2-propyl)benzamide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-n-(1-Hydroxy-2-Methyl-Propan-2-Yl)Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your most critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.