Description

4-(3-Chloro-2-Fluorophenyl)Benzaldehyde is a high-purity aromatic aldehyde building block, distinguished by its halogenated phenyl substituents. This compound is critical for synthesizing advanced pharmaceutical intermediates and functional organic materials due to its reactive aldehyde group and stable halogenated aromatic core. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the halogenated aromatic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the production of organic semiconductors, liquid crystals, and photoactive polymers.
• Custom Synthesis & Contract Research: A valuable building block for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences sector.
• Academic Research: Utilized in university and institutional labs for methodological studies in cross-coupling and organofluorine chemistry.

Basic Information

Product Name	4-(3-Chloro-2-Fluorophenyl)Benzaldehyde
CAS No.	342889-39-8
Molecular Formula	C13H8ClFO
Molecular Weight	234.65 g/mol
Synonyms	4-(3-Chloro-2-fluorophenyl)benzaldehyde; [1,1'-Biphenyl]-4-carboxaldehyde, 3'-chloro-2'-fluoro-; 3'-Chloro-2'-fluoro[1,1'-biphenyl]-4-carboxaldehyde; 4-(3-Chloro-2-fluorophenyl)benzenecarbaldehyde; 2-Fluoro-3-chloro-4'-formylbiphenyl; (3-Chloro-2-fluorophenyl)benzaldehyde-4; 4-Formyl-3'-chloro-2'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-2-Fluorophenyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for each lot, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.