Description

Diethyl 2-Bromo-5-Chloroterephthalate is a high-purity, specialty organic intermediate characterized by its bromo- and chloro-substituted terephthalate ester structure. This compound is valued for its precise reactivity, which enables the controlled synthesis of complex molecules in advanced chemical processes. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Precursor: Serves as a critical intermediate for creating functional organic molecules used in electronic displays and optoelectronic devices.
• Polymer & Dye Intermediate: Employed in the development of specialty polymers, high-performance plastics, and complex organic dyes and pigments.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions, such as Suzuki or Heck couplings, for constructing biaryl systems.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	Diethyl 2-Bromo-5-Chloroterephthalate
CAS No.	340148-60-9
Molecular Formula	C12H12BrClO4
Molecular Weight	335.58 g/mol
Synonyms	1,4-Benzenedicarboxylic acid, 2-bromo-5-chloro-, 1,4-diethyl ester; Diethyl 2-bromo-5-chlorobenzene-1,4-dicarboxylate; 2-Bromo-5-chloroterephthalic acid diethyl ester; Terephthalic acid, 2-bromo-5-chloro-, diethyl ester; Ethyl 2-bromo-5-chloroterephthalate
EINECS	Contact for details

Quality Control

Every batch of Diethyl 2-Bromo-5-Chloroterephthalate is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed control of related substances. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.