Description

2-Methyl-2-(4-Nitro-3-[(Phenylsulfonyl)Methyl]Phenyl)-1,3-Dioxolane is a specialized organic intermediate featuring a unique dioxolane-protected carbonyl group adjacent to a nitro and phenylsulfonylmethyl-substituted aromatic ring. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials. The specific molecular architecture offers valuable synthetic handles for further selective chemical transformations.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting neurological or inflammatory pathways.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides where the nitro and sulfone functionalities are essential for bioactivity.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers, coatings, or liquid crystals with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic molecules, leveraging the reactivity of the protected aldehyde and nitroarene groups.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular processes.

Basic Information

Product Name	2-Methyl-2-(4-Nitro-3-[(Phenylsulfonyl)Methyl]Phenyl)-1,3-Dioxolane
CAS No.	339276-49-2
Molecular Formula	C18H19NO6S
Molecular Weight	377.41 g/mol
Synonyms	4-Nitro-3-[(phenylsulfonyl)methyl]benzaldehyde dimethyl acetal; 1,3-Dioxolane, 2-methyl-2-[4-nitro-3-[(phenylsulfonyl)methyl]phenyl]-; 2-[4-Nitro-3-(phenylsulfonylmethyl)phenyl]-2-methyl-1,3-dioxolane; Benzaldehyde, 4-nitro-3-[(phenylsulfonyl)methyl]-, dimethyl acetal; (4-Nitro-3-((phenylsulfonyl)methyl)phenyl)acetaldehyde dimethyl acetal derivative
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-(4-Nitro-3-[(Phenylsulfonyl)Methyl]Phenyl)-1,3-Dioxolane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.