Description

n-[3,5-Bis(Trifluoromethyl)Phenyl]-2-[(2-Methylpropyl)Thio]-4-Pyridinecarboxamide is a high-value, fluorinated pyridine derivative of significant interest in advanced chemical synthesis. This compound matters as a sophisticated building block, offering unique steric and electronic properties conferred by its trifluoromethylphenyl and thioether substituents. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in areas requiring enhanced metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Material Science: Acts as a specialty monomer or additive in the development of advanced polymers with specific optical or surface properties.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research due to its distinct structural signature.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and other complex organic transformations to introduce the bis(trifluoromethyl)phenyl moiety.

Basic Information

Product Name	n-[3,5-Bis(Trifluoromethyl)Phenyl]-2-[(2-Methylpropyl)Thio]-4-Pyridinecarboxamide
CAS No.	339181-24-7
Molecular Formula	C18H15F6N2OS
Molecular Weight	421.38 g/mol
Synonyms	2-[(2-Methylpropyl)thio]-N-[3,5-bis(trifluoromethyl)phenyl]-4-pyridinecarboxamide; 4-Pyridinecarboxamide, N-[3,5-bis(trifluoromethyl)phenyl]-2-[(2-methylpropyl)thio]-; BTTMP; CAS 339181-24-7; n-(3,5-Bis(trifluoromethyl)phenyl)-2-(isobutylthio)isonicotinamide
EINECS	Contact for details

Quality Control

Our production of n-[3,5-Bis(Trifluoromethyl)Phenyl]-2-[(2-Methylpropyl)Thio]-4-Pyridinecarboxamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceable documentation supports your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.