Description

2-Amino-1-(3,5-Difluoro-Phenyl)-Ethanone is a high-purity, specialized organic building block featuring a reactive amino ketone functional group flanked by fluorine substituents. This compound matters for its role as a critical intermediate in the synthesis of complex, fluorinated molecules, offering a strategic entry point for introducing both amine and carbonyl reactivity. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients and functional materials where the fluorine atoms enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, including kinase inhibitors, CNS-active compounds, and anti-infective agents.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and pesticides where the difluorophenyl moiety contributes to improved lipophilicity and target activity.
• Ligand & Catalyst Development: Serves as a precursor for chelating ligands and organocatalysts in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to modify solubility and electronic properties.
• Chemical Biology Probes: Useful for creating fluorescent tags, affinity labels, and other molecular probes that leverage the amine group for conjugation.

Basic Information

Product Name	2-Amino-1-(3,5-Difluoro-Phenyl)-Ethanone
CAS No.	339001-26-2
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	1-(3,5-Difluorophenyl)-2-aminoethanone; 2-Amino-1-(3,5-difluorophenyl)ethan-1-one; 3',5'-Difluoro-2-aminoacetophenone; 2-Amino-3',5'-difluoroacetophenone; α-Amino-3,5-difluoroacetophenone; 3,5-Difluoro-2-aminoacetophenone; Ethanone, 2-amino-1-(3,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(3,5-Difluorophenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports cGMP and ISO 9001 standards for reliable, batch-to-batch consistency essential for R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.