Description

2-Methylfurane-5-Boronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a protected boronic acid derivative, essential for modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in pharmaceutical and advanced materials research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing novel drug candidates, particularly in the development of heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require specific furan-based structures.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including light-emitting diodes (OLEDs) and conductive polymers.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol ester group offers enhanced stability, making this reagent ideal for coupling with aryl/heteroaryl halides or triflates under standard palladium catalysis.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules or creating molecular probes for diagnostic applications.

Basic Information

Item	Details
Product Name	2-Methylfurane-5-Boronic Acid Pinacol Ester
CAS No.	338998-93-9
Molecular Formula	C11H19BO3
Molecular Weight	210.08 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylfuran; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan; 2-Methylfuran-5-boronic acid pinacol ester; 2-Methyl-5-furanboronic acid pinacol ester; 2-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)furan; 2-Methyl-5-boronofuran pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methylfurane-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.