Description

2-[5-(4-Methoxybenzoyl)-2-Thienyl]-3-Phenylacrylonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and inflammation. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs. Its precise molecular architecture makes it a valuable building block for synthesizing targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Kinase Inhibitor Development: Serves as a critical component in the research of potential kinase inhibitors for cancer and inflammatory diseases.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex, high-value specialty chemicals.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting cutting-edge drug discovery projects.

Basic Information

Product Name	2-[5-(4-Methoxybenzoyl)-2-Thienyl]-3-Phenylacrylonitrile
CAS No.	338966-79-3
Molecular Formula	C22H15NO2S
Molecular Weight	357.42 g/mol
Synonyms	3-Phenyl-2-[5-(4-methoxybenzoyl)thiophen-2-yl]acrylonitrile; (2E)-2-[5-(4-Methoxybenzoyl)-2-thienyl]-3-phenyl-2-propenenitrile; 2-(5-(4-Methoxybenzoyl)thiophen-2-yl)-3-phenylacrylonitrile; 338966-79-3; 2-[5-(p-Methoxybenzoyl)-2-thienyl]-3-phenylacrylonitrile; AKOS005258555; Thiophene-based acrylonitrile derivative; 4-Methoxybenzoyl thiophene acrylonitrile
EINECS	Contact for details

Quality Control

Our 2-[5-(4-Methoxybenzoyl)-2-Thienyl]-3-Phenylacrylonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and traceability for demanding pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.