Description

8-Chloro-3-Styryl-6-(Trifluoromethyl)[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, multi-functional heterocyclic compound featuring a unique triazolopyridine core substituted with chloro, styryl, and trifluoromethyl groups. This molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-inflammatory agents.
• Agrochemical Research: Serves as a building block for developing new generation pesticides, herbicides, and fungicides, leveraging the bioactivity of the triazolopyridine scaffold.
• Material Science Precursor: Used in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated styryl system and electron-withdrawing trifluoromethyl group.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Product Name	8-Chloro-3-Styryl-6-(Trifluoromethyl)[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	338795-37-2
Molecular Formula	C15H9ClF3N3
Molecular Weight	323.70 g/mol
Synonyms	8-Chloro-3-styryl-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine; 338795-37-2; 6-(Trifluoromethyl)-8-chloro-3-styryl-[1,2,4]triazolo[4,3-a]pyridine; 3-Styryl-8-chloro-6-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridine; [1,2,4]Triazolo[4,3-a]pyridine, 8-chloro-3-(2-phenylethenyl)-6-(trifluoromethyl)-; 8-Chloro-3-[(E)-2-phenylethenyl]-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our high-purity intermediates. Every batch of 8-Chloro-3-Styryl-6-(Trifluoromethyl)[1,2,4]Triazolo[4,3-A]Pyridine is analyzed using advanced techniques like HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to support cGMP compliance for pharmaceutical applications, and we can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.