Description

1-[3-(Trifluoromethyl)Benzyl]Pyridin-2-One-5-Carboxylic Acid 97% is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its trifluoromethyl benzyl moiety imparts desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Benzyl]Pyridin-2-One-5-Carboxylic Acid 97%
CAS No.	338783-19-0
Molecular Formula	C14H10F3NO3
Molecular Weight	297.23 g/mol
Synonyms	5-Carboxy-1-[(3-trifluoromethyl)benzyl]-2-pyridone; 1-[(3-Trifluoromethyl)benzyl]-2-oxo-1,2-dihydropyridine-5-carboxylic Acid; 1-(3-Trifluoromethylbenzyl)-2-oxo-1,2-dihydropyridine-5-carboxylic Acid; 1-(α,α,α-Trifluoro-m-tolyl)methyl-2-pyridone-5-carboxylic Acid; 2-Pyridone-5-carboxylic acid, 1-[(3-trifluoromethyl)benzyl]-; 338783-19-0; 1-(3-(Trifluoromethyl)benzyl)-2-oxo-1,2-dihydropyridine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Benzyl]Pyridin-2-One-5-Carboxylic Acid 97% is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the specified standard of ≥97% purity. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.