Description

Ethyl 4-[(4-Fluoroanilino)Carbonyl]-5-Methyl-3-Isoxazolecarboxylate is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique isoxazole core is a valuable structural motif. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Serves as a key scaffold for developing new generation herbicides, fungicides, or insecticides with improved efficacy and selectivity.
• Chemical Biology Probe Synthesis: Used to create specialized molecular tools for studying enzyme function and biological pathways in academic and industrial research.
• Material Science Applications: Potential use as a monomer or additive in the development of advanced polymers with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	Ethyl 4-[(4-Fluoroanilino)Carbonyl]-5-Methyl-3-Isoxazolecarboxylate
CAS No.	338761-30-1
Molecular Formula	C14H13FN2O4
Molecular Weight	292.26 g/mol
Synonyms	Ethyl 5-methyl-4-[[(4-fluorophenyl)amino]carbonyl]isoxazole-3-carboxylate; 3-Isoxazolecarboxylic acid, 4-[[(4-fluorophenyl)amino]carbonyl]-5-methyl-, ethyl ester; 4-[(4-Fluoroanilino)carbonyl]-5-methyl-3-isoxazolecarboxylic acid ethyl ester; Ethyl 4-(4-fluorophenylcarbamoyl)-5-methylisoxazole-3-carboxylate; 338761-30-1; AI3-52711; CTK8G0187
EINECS	Contact for details

Quality Control

Our Ethyl 4-[(4-Fluoroanilino)Carbonyl]-5-Methyl-3-Isoxazolecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.