Description

1-Methyl-2-([3-(Trifluoromethyl)Phenyl]Sulfanyl)-1H-Indole-3-Carbaldehyde is a high-value, multi-functional indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical, agrochemical, and advanced material research and development teams need this precise chemical building block to drive innovation in drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the indole and trifluoromethyl motifs for enhanced biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic methodology and heterocyclic chemistry research.
• Fine Chemical Synthesis: Intermediate for the production of complex dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-Methyl-2-([3-(Trifluoromethyl)Phenyl]Sulfanyl)-1H-Indole-3-Carbaldehyde
CAS No.	338416-52-7
Molecular Formula	C17H12F3NOS
Molecular Weight	335.35 g/mol
Synonyms	1-Methyl-2-[(3-trifluoromethylphenyl)thio]-1H-indole-3-carboxaldehyde; 2-[(3-Trifluoromethylphenyl)thio]-1-methyl-1H-indole-3-carbaldehyde; 1-Methyl-2-(3-trifluoromethylphenylsulfanyl)-1H-indole-3-carbaldehyde; 3-Formyl-1-methyl-2-[(3-trifluoromethylphenyl)thio]indole; CAS 338416-52-7; 1-Methyl-2-(α,α,α-trifluoro-m-tolylthio)indole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-Methyl-2-([3-(Trifluoromethyl)Phenyl]Sulfanyl)-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and advanced research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.