Description

1-(4-Chlorobenzyl)-2-(2-Chloro-3-Pyridinyl)-1H-1,3-Benzimidazole is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzimidazole-based active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Essential building block for medicinal chemistry research, enabling the creation of new chemical entities for biological screening.
• Agrochemical Research: Potential intermediate in the development of new fungicides or pesticides due to its benzimidazole core structure.
• Material Science: Used in research for creating specialty polymers or organic electronic materials with specific functional properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-(4-Chlorobenzyl)-2-(2-Chloro-3-Pyridinyl)-1H-1,3-Benzimidazole
CAS No.	338411-33-9
Molecular Formula	C19H13Cl2N3
Molecular Weight	354.23 g/mol
Synonyms	1-[(4-Chlorophenyl)methyl]-2-(2-chloro-3-pyridinyl)-1H-benzimidazole; 2-(2-Chloro-3-pyridinyl)-1-[(4-chlorophenyl)methyl]-1H-benzimidazole; 1-(4-Chlorobenzyl)-2-(2-chloro-3-pyridinyl)benzimidazole; 338411-33-9; 1H-Benzimidazole, 1-[(4-chlorophenyl)methyl]-2-(2-chloro-3-pyridinyl)-; 2-(2-Chloro-3-pyridyl)-1-(4-chlorobenzyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorobenzyl)-2-(2-Chloro-3-Pyridinyl)-1H-1,3-Benzimidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical R&D and scale-up processes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for impurity identification and control, and our quality standards are designed to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.