Description

1-[2-(4-Fluorophenyl)Cyclopropyl]-1-Ethanone is a high-purity fluorinated organic building block with a unique cyclopropyl ketone structure. This compound is valued for its role as a critical intermediate in advanced synthetic chemistry, enabling the development of novel molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific stereochemistry and fluorine substitution are key design features.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorophenyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to the development of materials with specific optical or electronic properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via reactions involving the ketone and strained cyclopropane ring.
• Fluorine Chemistry Studies: Utilized as a model compound in research exploring the effects of fluorine substitution on reaction kinetics and molecular conformation.

Basic Information

Product Name	1-[2-(4-Fluorophenyl)Cyclopropyl]-1-Ethanone
CAS No.	338392-56-6
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	1-(2-(4-Fluorophenyl)cyclopropyl)ethanone; 2-(4-Fluorophenyl)cyclopropyl methyl ketone; 4-Fluoro-α-methylcyclopropylbenzene; 1-Acetyl-2-(4-fluorophenyl)cyclopropane; (2-(4-Fluorophenyl)cyclopropyl)methyl ketone; 4-Fluorophenyl cyclopropyl ketone derivative
EINECS	Contact for details

Quality Control

Our production of 1-[2-(4-Fluorophenyl)Cyclopropyl]-1-Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality system is designed to support cGMP-compliant applications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere such as nitrogen or argon is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.