Description

(1R,2R)-trans-1-Hydroxy-1,2-Dihydro-2-Naphthyl Benzoate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of enantiomerically pure pharmaceuticals and fine chemicals, where stereochemical integrity is paramount. Industries that require it include pharmaceutical R&D, contract manufacturing organizations (CMOs), and specialty chemical producers focused on developing novel active pharmaceutical ingredients (APIs) and complex molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereoselectivity.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex, value-added molecules in agrochemical and material science research.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in chiral separation techniques like HPLC and SFC.

Basic Information

Product Name	(1R,2R)-trans-1-Hydroxy-1,2-Dihydro-2-Naphthyl Benzoate
CAS No.	337376-51-9
Molecular Formula	C17H14O3
Molecular Weight	266.29 g/mol
Synonyms	(1R,2R)-1,2-Dihydro-1-hydroxy-2-naphthyl benzoate; (1R,2R)-1-Hydroxy-1,2-dihydronaphthalen-2-yl benzoate; Benzoic acid (1R,2R)-1,2-dihydro-1-hydroxy-2-naphthyl ester; (1R,2R)-trans-1,2-Dihydro-1-hydroxy-2-naphthyl benzoate; (1R,2R)-1,2-Dihydro-1-hydroxy-2-naphthalenyl benzoate; (1R,2R)-HDB; trans-(1R,2R)-HDB
EINECS	Contact for details

Quality Control

Our (1R,2R)-trans-1-Hydroxy-1,2-Dihydro-2-Naphthyl Benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chiral purity. Production adheres to cGMP guidelines where applicable, and all materials are supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.