Description

D-Erythro-Pentaric Acid, 3,4-Dideoxy-3-Methyl-, 5,2-Lactone, 1-Methyl Ester is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its complex stereochemistry and functionalized lactone structure make it a valuable precursor for the development of novel pharmaceuticals, agrochemicals, and fine chemicals. This high-purity compound is primarily utilized by research institutions and industrial R&D departments focused on asymmetric synthesis, medicinal chemistry, and the production of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and anticancer research.
• Agrochemical Development: Used in the research and production of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for creating novel chiral ligands and catalysts used in enantioselective transformations.
• Natural Product Synthesis: An important building block for the total or semi-synthesis of complex natural products containing deoxy sugar or lactone motifs.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial Research: A critical reagent for methodological development in organic chemistry and for probing structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	D-Erythro-Pentaric Acid, 3,4-Dideoxy-3-Methyl-, 5,2-Lactone, 1-Methyl Ester
CAS No.	337365-73-8
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	1-Methyl 3,4-dideoxy-3-methyl-D-erythro-pentaro-5,2-lactonate; Methyl 3,4-dideoxy-3-methyl-D-erythro-pentaro-5,2-lactonate; 1-Methyl ester of 3,4-dideoxy-3-methyl-D-erythro-pentaric acid 5,2-lactone; D-erythro-Pentaric acid, 3,4-dideoxy-3-methyl-, 5,2-lactone, 1-methyl ester; (3R,5S)-5-(Hydroxymethyl)-3-methyloxolan-2-one methyl derivative; A chiral deoxy sugar lactone derivative.
EINECS	Contact for details

Quality Control

Every batch of D-Erythro-Pentaric Acid, 3,4-Dideoxy-3-Methyl-, 5,2-Lactone, 1-Methyl Ester is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including chiral purity verification by HPLC, is performed. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.