Description

Methyl 5-Cyano-2-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its molecular structure, featuring both cyano and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzoate core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into specialty polymers to alter their thermal, chemical, and surface properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl systems.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in academic and industrial R&D laboratories.

Basic Information

Product Name	Methyl 5-Cyano-2-Fluorobenzoate
CAS No.	337362-21-7
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	2-Fluoro-5-cyanobenzoic acid methyl ester; Methyl 2-fluoro-5-cyanobenzoate; 5-Cyano-2-fluorobenzoic acid methyl ester; Benzoic acid, 5-cyano-2-fluoro-, methyl ester; Methyl 5-cyano-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Cyano-2-Fluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.