Description

4-[2-(Boc-Amino)-2-Propyl]Phenylboronic Acid Pinacol Ester is a sophisticated, high-purity boronic ester derivative designed for advanced organic synthesis and pharmaceutical research. This compound serves as a critical protected intermediate, enabling the controlled introduction of functionalized aryl groups in complex molecule construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring complex biaryl structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, protected boronic ester reagent for palladium-catalyzed carbon-carbon bond formation, essential for creating novel chemical libraries.
• Peptide & Protein Conjugation: Used in the development of bioconjugates and antibody-drug conjugates (ADCs) where controlled linkage is required.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides with specific aryl motifs.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or OFETs.
• Chemical Biology Probes: Utilized to synthesize tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	4-[2-(Boc-Amino)-2-Propyl]Phenylboronic Acid Pinacol Ester
CAS No.	335592-60-4
Molecular Formula	C20H32BNO4
Molecular Weight	361.29 g/mol
Synonyms	tert-Butyl N-[2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-yl]carbamate; 4-[2-[(tert-Butoxycarbonyl)amino]-2-propyl]benzeneboronic Acid Pinacol Ester; Boc-Protected Aminophenylboronic Acid Pinacol Ester; (4-(2-((tert-Butoxycarbonyl)amino)propan-2-yl)phenyl)boronic Acid Pinacol Ester; 2-(4-(2-((tert-Butoxycarbonyl)amino)propan-2-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-[2-(Boc-Amino)-2-Propyl]Phenylborboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.