Description

3Ah-Indene-3A-Carbonitrile,1,2,3,4,5,6-Hexahydro-7-Methyl-6-Oxo-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex, functionalized indene core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in process development and scale-up for new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules targeting specific biological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a standard for developing and validating robust, scalable manufacturing routes for APIs.
• Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in academic and industrial research to construct novel heterocyclic compounds and complex molecular architectures.

Basic Information

Product Name	3Ah-Indene-3A-Carbonitrile,1,2,3,4,5,6-Hexahydro-7-Methyl-6-Oxo-(9Ci)
CAS No.	335421-62-0
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	1,2,3,4,5,6-Hexahydro-7-methyl-6-oxo-3aH-indene-3a-carbonitrile; 3aH-Indene-3a-carbonitrile, 1,2,3,4,5,6-hexahydro-7-methyl-6-oxo-; 7-Methyl-6-oxo-1,2,3,4,5,6-hexahydro-3aH-indene-3a-carbonitrile; Hexahydro-7-methyl-6-oxo-3aH-indene-3a-carbonitrile
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.