Description

4H-Inden-4-One, 6-Acetyloctahydro-3A,5-Dihydroxy-, (3Ar,5S,6S,7Ar)-Rel- (9Ci) is a complex, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its intricate polycyclic structure with multiple functional groups makes it a valuable chiral building block for constructing pharmacologically active molecules. This high-purity compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel drug candidates and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs for structure-activity relationship (SAR) studies and library synthesis.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce complex molecular architecture due to its defined stereocenters at the 3A, 5, 6, and 7A positions.
• Fine Chemical Production: Acts as a starting material or intermediate for the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development in total synthesis and catalysis.
• Process Chemistry Development: Investigated for scale-up and optimization of synthetic routes to more complex molecules in pilot plant settings.

Basic Information

Item	Detail
Product Name	4H-Inden-4-One, 6-Acetyloctahydro-3A,5-Dihydroxy-, (3Ar,5S,6S,7Ar)-Rel- (9Ci)
CAS No.	335388-81-3
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	rel-(3aR,5S,6S,7aR)-6-Acetyloctahydro-3a,5-dihydroxy-4H-inden-4-one; (3aR,5S,6S,7aR)-6-Acetyl-3a,5-dihydroxyoctahydro-4H-inden-4-one; 6-Acetyloctahydro-3a,5-dihydroxy-4H-inden-4-one (rel); Octahydro-4H-inden-4-one derivative; Chiral Indanone Derivative; Polyhydroxy Indanone Intermediate
EINECS	Contact for details

Quality Control

Our 4H-Inden-4-One, 6-Acetyloctahydro-3A,5-Dihydroxy-, (3Ar,5S,6S,7Ar)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.