Description

2-(2,4,6-Trimethoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane is a specialized organoboron compound featuring a trimethoxyphenyl group, which serves as a key synthetic intermediate in advanced organic synthesis. This compound is valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing drug candidates, particularly those containing complex aryl-aryl bonds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific aryl motifs.
• Material Science: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics.
• Chemical Synthesis: Acts as a versatile boron reagent in palladium-catalyzed cross-coupling reactions to create novel chemical entities.
• Academic & R&D: A valuable tool for methodological development and exploring new reaction pathways in university and industrial laboratories.

Basic Information

Product Name	2-(2,4,6-Trimethoxyphenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	335343-08-3
Molecular Formula	C15H21BO5
Molecular Weight	292.14 g/mol
Synonyms	2,4,6-Trimethoxyphenylboronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 5,5-Dimethyl-2-(2,4,6-trimethoxyphenyl)-1,3,2-dioxaborinane; Trimethoxyphenyl MIDA Boronate; (2,4,6-Trimethoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; TMOP-MIDA Boronate; CAS 335343-08-3
EINECS	Contact for details

Quality Control

Our production of 2-(2,4,6-Trimethoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.