Description

4,4,5,5-Tetramethyl-2-(2'-Methyl-Biphenyl-4-Yl)-[1,3,2]Dioxaborolane is a high-value, advanced boronic ester intermediate essential for modern synthetic chemistry. This compound is a critical building block in cross-coupling reactions, enabling the efficient construction of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl structures, a common motif in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating novel drug candidates with complex aromatic systems.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides that require specific biphenyl architectures.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport materials and emissive layer components for display and lighting technologies.
• Ligand and Catalyst Development: Useful for constructing sophisticated ligand frameworks in organometallic chemistry and catalysis.
• Material Science Research: A building block for creating novel polymers, liquid crystals, and other functional organic materials with tailored properties.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2'-Methyl-Biphenyl-4-Yl)-[1,3,2]Dioxaborolane
CAS No.	335233-26-6
Molecular Formula	C20H25BO2
Molecular Weight	308.22 g/mol
Synonyms	2-(2'-Methyl-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(4-(2-Methylphenyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2'-Methylbiphenyl-4-boronic acid pinacol ester; 2-Methylbiphenyl-4-ylboronic acid pinacol ester; (2'-Methylbiphenyl-4-yl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[4-(2-methylphenyl)phenyl]-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2'-Methyl-Biphenyl-4-Yl)-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistent performance in sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize degradation. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.