Description

1-Pentanone, 2,2-Difluoro-1-(3-Furanyl)-3-Hydroxy-4-Methyl- (9Ci) is a specialized fluorinated ketone building block with a unique furan-substituted structure. This compound is valued for its role as a key chiral intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents, particularly for complex small-molecule drugs.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoro and furan motifs can contribute to biological activity.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced materials with tailored properties.
• Organic Chemistry Research: Employed in academic and industrial R&D for methodology development and the synthesis of complex natural product analogs.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Pentanone, 2,2-Difluoro-1-(3-Furanyl)-3-Hydroxy-4-Methyl- (9Ci)
CAS No.	334873-76-6
Molecular Formula	C10H12F2O3
Molecular Weight	218.20 g/mol
Synonyms	2,2-Difluoro-1-(3-furanyl)-3-hydroxy-4-methyl-1-pentanone; 2,2-Difluoro-3-hydroxy-4-methyl-1-(3-furyl)-1-pentanone; 1-Pentanone, 2,2-difluoro-1-(3-furanyl)-3-hydroxy-4-methyl-; 334873-76-6; 2,2-Difluoro-1-(furan-3-yl)-3-hydroxy-4-methylpentan-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, chiral purity, and identity confirmation via NMR and MS. Certificates of Analysis (COA) are available upon request to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.