Description

(2S,3S)-Ethyl 3-(Propylcarbamoyl)Oxirane-2-Carboxylate is a high-purity chiral epoxide derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in asymmetric synthesis. Its defined stereochemistry is essential for constructing complex molecules with high enantiomeric purity, directly impacting the efficacy and safety profile of final active ingredients. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel therapeutics and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other bioactive molecules requiring specific stereocenters.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions, including nucleophilic ring-opening, to introduce the (2S,3S) configuration into target compounds.
• Agrochemical Research: Intermediate in the development of enantiomerically pure pesticides and herbicides where specific isomer activity is required.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that utilize chiral epoxide chemistry.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and catalysis focused on epoxide transformations.

Basic Information

Product Name	(2S,3S)-Ethyl 3-(Propylcarbamoyl)Oxirane-2-Carboxylate
CAS No.	334772-27-9
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Ethyl (2S,3S)-3-[(propylamino)carbonyl]oxirane-2-carboxylate; (2S,3S)-Ethyl 3-(propylaminocarbonyl)oxirane-2-carboxylate; (2S,3S)-Ethyl 3-(n-propylcarbamoyl)glycidate; Propylcarbamoyl oxirane carboxylate ethyl ester; (2S,3S)-Glycidic acid, 3-[(propylamino)carbonyl]-, ethyl ester; Chiral ethyl glycidate derivative; (2S,3S)-Epoxide carboxamide ester
EINECS	Contact for details

Quality Control

Our (2S,3S)-Ethyl 3-(Propylcarbamoyl)Oxirane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity compliant with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.