Description

3-{4-Nitrophenyl}-2-[2-(3-Pyridinyl)Vinyl]-4(3H)-Quinazolinone is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound matters as a critical building block in medicinal chemistry research, particularly for the synthesis of novel drug candidates targeting various therapeutic areas. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical suppliers engaged in developing kinase inhibitors, anti-cancer agents, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel quinazolinone-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Kinase Inhibitor Development: A valuable scaffold for creating compounds that modulate kinase activity, relevant in oncology and inflammatory disease research.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing of complex, high-value organic molecules.
• Academic Research: Used in university and institutional labs for heterocyclic chemistry studies and the discovery of new bioactive compounds.

Basic Information

Product Name	3-{4-Nitrophenyl}-2-[2-(3-Pyridinyl)Vinyl]-4(3H)-Quinazolinone
CAS No.	334505-36-1
Molecular Formula	C21H14N4O3
Molecular Weight	370.36 g/mol
Synonyms	3-(4-Nitrophenyl)-2-[(E)-2-(pyridin-3-yl)ethenyl]-4(3H)-quinazolinone; 2-[(E)-2-(3-Pyridinyl)ethenyl]-3-(4-nitrophenyl)-4(3H)-quinazolinone; 3-(4-Nitrophenyl)-2-[2-(3-pyridinyl)vinyl]-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 3-(4-nitrophenyl)-2-[2-(3-pyridinyl)vinyl]-; (E)-3-(4-Nitrophenyl)-2-(2-(pyridin-3-yl)vinyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our 3-{4-Nitrophenyl}-2-[2-(3-Pyridinyl)Vinyl]-4(3H)-Quinazolinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.