Description

6-Chloro-2-Methylamino-3-Nitrobenzonitrile is a specialized aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, methylamino, and nitro substituents, makes it a versatile intermediate for constructing complex molecular architectures. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its nitro and chloro functional groups.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized azo dyes and high-performance pigments due to its aromatic nitrobenzonitrile core.
• Material Science Research: Intermediate in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	6-Chloro-2-Methylamino-3-Nitrobenzonitrile
CAS No.	333458-39-2
Molecular Formula	C9H7ClN3O2
Molecular Weight	224.63 g/mol
Synonyms	2-Amino-6-chloro-3-nitrobenzonitrile, N-Methyl Derivative; 2-Methylamino-6-chloro-3-nitrobenzonitrile; 3-Nitro-6-chloro-2-(methylamino)benzonitrile; Benzonitrile, 6-chloro-2-(methylamino)-3-nitro-; 6-Chloro-2-(methylamino)-3-nitrobenzonitrile; CAS 333458-39-2
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Methylamino-3-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its chemical structure, the material should be considered moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.