Description

[(3-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester is a high-purity, synthetic organic compound designed for advanced chemical synthesis and pharmaceutical research. This specialized intermediate is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It serves as a key building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bromo-phenyl and sulfonamide functional groups.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to introduce complex aryl-sulfonamide motifs.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and advanced organic materials.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.

Basic Information

Product Name	[(3-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester
CAS No.	333450-61-6
Molecular Formula	C₁₆H₁₆BrNO₄S
Molecular Weight	398.27 g/mol
Synonyms	Methyl [(3-bromophenyl)(4-methylphenyl)sulfonylamino]acetate; Methyl 2-[[(3-bromophenyl)-(4-tolylsulfonyl)amino]]acetate; N-[(3-Bromophenyl)(4-methylphenyl)sulfonyl]glycine Methyl Ester; Methyl N-[(3-bromophenyl)-p-toluenesulfonylamido]acetate; 333450-61-6; (3-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino-Acetic Acid Methyl Ester; Tosyl-protected bromophenyl glycine methyl ester
EINECS	Contact for details

Quality Control

Our production of [(3-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality system is designed to support cGMP requirements for pharmaceutical intermediates, ensuring traceability and documentation excellence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.