Description

(4-Chlorocarbonylphenyl)Boronic Anhydride is a high-value bifunctional organoboron building block that serves as a critical precursor in advanced synthetic chemistry. Its unique structure, featuring both a reactive acid chloride and a boronic anhydride moiety, enables efficient, one-pot derivatization and cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as in materials science for creating functional polymers and organic electronic components.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex molecules via Suzuki-Miyaura cross-coupling, enabling the creation of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific aryl-boronate functionalization.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers, liquid crystals, and organic semiconductors with tailored properties.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation, labeling biomolecules, or creating activity-based probes for enzyme studies.
• Organic Synthesis Reagent: Acts as a versatile precursor for generating a wide array of functionalized boronic acids and esters for further synthetic transformations.
• Metal-Organic Framework (MOF) Construction: Employed as a linker molecule to create novel porous materials for gas storage, separation, or catalysis.

Basic Information

Product Name	(4-Chlorocarbonylphenyl)Boronic Anhydride
CAS No.	332154-57-1
Molecular Formula	C14H8BClO4
Molecular Weight	286.48 g/mol
Synonyms	4-(Chlorocarbonyl)phenylboronic Anhydride; 4-Carboxybenzene Boronic Anhydride Chloride; 4-(Chloroformyl)phenylboronic Acid Cyclic Anhydride; 1,3,5,2,4-Trioxadiborolane, 2,4-Bis[4-(chlorocarbonyl)phenyl]-; 4-(Chlorocarbonyl)benzeneboronic Anhydride; Boronic acid, B,B'-[1,4-phenylenebis(carbonylimino)]bis[4-(chlorocarbonyl)phenyl]-; 4-Formylbenzeneboronic Acid Chloride Anhydride
EINECS	Contact for details

Quality Control

Our (4-Chlorocarbonylphenyl)Boronic Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from incompatible materials such as strong bases, oxidizing agents, and moisture sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.