Description

1,3-Dioxepane-4-Carboxaldehyde,2-(1-Methylethyl)-,(2R,4R)-(9Ci) is a specialized chiral building block and aldehyde derivative of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in constructing heterocyclic cores.
• Asymmetric Synthesis: Utilized as a precursor in stereoselective reactions, including aldol condensations and reductive aminations, to introduce the (2R,4R)-configured moiety.
• Agrochemical Research: Serves as a building block for developing new chiral active ingredients for crop protection products.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for transition metal catalysis.
• Academic & Industrial R&D: Employed in methodological studies and the synthesis of complex natural product analogs or novel materials.
• Fine Chemical Production: Applied in the custom synthesis of high-value, specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	1,3-Dioxepane-4-Carboxaldehyde,2-(1-Methylethyl)-,(2R,4R)-(9Ci)
CAS No.	332115-42-1
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	(2R,4R)-2-Isopropyl-1,3-dioxepane-4-carboxaldehyde; (2R,4R)-2-(1-Methylethyl)-1,3-dioxepane-4-carbaldehyde; (2R,4R)-2-Isopropyl-1,3-dioxepane-4-carbaldehyde; 4-Carboxaldehyde-2-isopropyl-1,3-dioxepane, (2R,4R)-; (2R,4R)-2-Isopropyl-1,3-dioxepane-4-carboxaldehyde (9CI); 1,3-Dioxepane-4-carboxaldehyde, 2-(1-methylethyl)-, (2R,4R)-; Chiral 1,3-dioxepane aldehyde derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), with specifications tailored to research and development needs. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and other relevant parameters are available upon request. Our quality system supports development under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and oxidation; consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.