Description

Tetrahydrofuran-3-Boronic Acid Pinacol Ester is a high-purity organoboron reagent featuring a tetrahydrofuran backbone, which is a valuable synthon in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs) via cross-coupling.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by introducing the tetrahydrofuran moiety into target molecules.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of specialized polymers and organic electronic materials.
• Chemical Biology & Medicinal Chemistry: Employed in the synthesis of molecular probes, enzyme inhibitors, and compound libraries for drug discovery programs.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Item	Details
Product Name	Tetrahydrofuran-3-Boronic Acid Pinacol Ester
CAS No.	331958-90-8
Molecular Formula	C10H19BO3
Molecular Weight	198.07 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)tetrahydrofuran; Tetrahydro-3-furanboronic Acid Pinacol Ester; 3-Tetrahydrofuranylboronic Acid Pinacol Ester; THF-3-Boronic Acid Pinacol Ester; 3-Borono-tetrahydrofuran Pinacol Ester; (Tetrahydrofuran-3-yl)boronic Acid Pinacol Ester; 3-(Pinacolatoboryl)tetrahydrofuran
EINECS	Contact for details

Quality Control

Our Tetrahydrofuran-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.