Description

n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Benzo[D]Oxazol-2-Amine is a high-value, advanced pharmaceutical intermediate and organic building block that combines a benzoxazole core with a pinacol boronate ester functional group. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules for drug discovery and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and OLED materials industries seeking to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing benzoxazole pharmacophores for oncology, CNS, and anti-infective applications.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester group makes it an excellent partner for palladium-catalyzed coupling with aryl/heteroaryl halides, facilitating carbon-carbon bond formation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require the benzoxazole scaffold for bioactivity.
• OLED and Electronic Materials: Serves as a precursor for constructing conjugated organic molecules used in light-emitting diodes (OLEDs) and other organic electronic devices.
• Ligand and Catalyst Development: The nitrogen and oxygen donor atoms in the benzoxazole ring can be utilized in the design of novel ligands for catalysis.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags or molecular probes for studying biological processes.

Basic Information

Item	Details
Product Name	n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Benzo[D]Oxazol-2-Amine
CAS No.	330793-73-2
Molecular Formula	C21H25BN2O3
Molecular Weight	364.25 g/mol
Synonyms	2-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)benzoxazole; 4-(Benzoxazol-2-ylamino)phenylboronic acid pinacol ester; 2-Amino-4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole; Benzo[d]oxazol-2-amine, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 330793-73-2; BRN 9086967; AOBP; 4-(2-Benzoxazolylamino)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Benzo[D]Oxazol-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider keeping the material under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.