Description

1-Methyl-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Benzo[D]Imidazol-2-Amine is a high-value, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound matters as a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for oncology and other targeted therapies.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key boronic ester reagent for constructing carbon-carbon bonds in drug discovery pipelines.
• Pharmaceutical Intermediate: For the synthesis of novel benzimidazole-based drug candidates targeting various disease pathways.
• Organic Light-Emitting Diode (OLED) Materials Research: As a precursor for developing electron-transport or emissive layer materials.
• Agrochemical Synthesis: In the research and development of new crop protection agents with complex heterocyclic structures.
• Ligand and Catalyst Development: For creating novel ligands used in catalytic systems or as functional components in metal-organic frameworks (MOFs).
• Academic and Industrial R&D: Serving as a versatile scaffold in combinatorial chemistry and high-throughput screening libraries.

Basic Information

Product Name	1-Methyl-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Benzo[D]Imidazol-2-Amine
CAS No.	330793-28-7
Molecular Formula	C20H24BN3O2
Molecular Weight	349.24 g/mol
Synonyms	1-Methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-benzimidazol-2-amine; 1-Methyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-benzo[d]imidazol-2-amine; 2-Amino-1-methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzimidazole; 330793-28-7; Benzimidazole, 1-methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 1-Methyl-2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 1-Methyl-n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Benzo[D]Imidazol-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.