Description

4-(Pyrimidin-2-Yloxy)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, where precise molecular structure is paramount.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for biological target identification.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis research.
• Custom Synthesis & Contract Manufacturing: Supplied as a high-quality starting material for bespoke synthesis projects and scale-up processes.

Basic Information

Item	Details
Product Name	4-(Pyrimidin-2-Yloxy)Phenylboronic Acid Pinacol Ester
CAS No.	330792-87-5
Molecular Formula	C₁₆H₁₉BN₂O₃
Molecular Weight	298.15 g/mol
Synonyms	2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)pyrimidine; 4-(Pyrimidin-2-yloxy)benzeneboronic acid pinacol ester; 4-(2-Pyrimidinyloxy)phenylboronic acid pinacol ester; [4-(Pyrimidin-2-yloxy)phenyl]boronic acid pinacol ester; Pinacol 4-(pyrimidin-2-yloxy)phenylboronate; B-[4-(2-Pyrimidinyloxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-(Pyrimidin-2-Yloxy)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.