Description

Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (Ii) is a highly sophisticated chiral ruthenium complex, specifically designed for asymmetric catalysis. This compound matters because it serves as a powerful and selective catalyst for enantioselective hydrogenation and other key transformations, enabling the production of single-enantiomer intermediates with high optical purity. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-value catalyst for the synthesis of chiral active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical control is critical.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and olefins in pharmaceutical intermediate synthesis.
• Pharmaceutical API Development: Production of chiral building blocks for drugs targeting central nervous system, cardiovascular, and metabolic diseases.
• Agrochemical Synthesis: Manufacture of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Catalyzing C-C and C-H bond formation reactions under mild conditions for specialty chemicals.
• Academic & Industrial Research: A benchmark catalyst for developing new asymmetric synthetic methodologies.
• Chiral Ligand Evaluation: Used in studies to assess the performance of modified BINAP and diamine ligand frameworks.

Basic Information

Product Name	Dichloro[(R)-(+)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(1S,2S)-(-)-1,2-Diphenylethylenediamine]Ruthenium (Ii)
CAS No.	329736-05-2
Molecular Formula	C58H48Cl2N2P2Ru
Molecular Weight	989.92 g/mol
Synonyms	RuCl2[(R)-BINAP][(1S,2S)-DPEN]; (R)-BINAP/(1S,2S)-DPEN-Ru(II) Dichloride; Dichloro[(R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl][(1S,2S)-1,2-diphenylethylenediamine]ruthenium; Noyori-Ikariya Catalyst; Ru-BINAP-DPEN Catalyst; Asymmetric Hydrogenation Catalyst Ru(BINAP)(DPEN)Cl2; Ruthenium(II) (R)-BINAP (S,S)-DPEN complex
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality management protocols to ensure exceptional purity and catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as metal content, chiral purity, and spectroscopic identity. Our quality systems support development under cGMP guidelines for pharmaceutical applications, ensuring traceability and consistency for critical process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., argon or nitrogen) to maintain stability and prevent decomposition. The container should be kept in a desiccator to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Ruthenium Content	10.0 - 10.5 %
Specific Rotation [α]D20	Contact for details
Solubility	Soluble in dichloromethane, toluene; slightly soluble in methanol
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.