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Dichloro[(R)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(R)-1,1-Bis(p-Methoxyphenyl)-2-Isopropylethane-1,2-Diamine]Ruthenium(Ii) CAS NO 329735-86-6
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CAS No.:329735-86-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Dichloro[(R)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(R)-1,1-Bis(p-Methoxyphenyl)-2-Isopropylethane-1,2-Diamine]Ruthenium(II) is a highly sophisticated, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a premier catalyst for enantioselective hydrogenation and transfer hydrogenation reactions, enabling the production of single-isomer intermediates with high optical purity. It is critically needed by R&D and production chemists in the pharmaceutical and fine chemical industries for synthesizing chiral active pharmaceutical ingredients (APIs) and advanced materials.
Application
- Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins to produce chiral alcohols and amines.
- Pharmaceutical Intermediate Synthesis: Key catalyst in the production of chiral building blocks for APIs, including β-amino acids and derivatives.
- Transfer Hydrogenation: Employed in reactions using hydrogen donors like isopropanol or formic acid for selective reductions under mild conditions.
- Fine Chemical Manufacturing: Enables the synthesis of high-value, enantiomerically pure compounds for agrochemicals, flavors, and fragrances.
- Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
- Process Chemistry Optimization: Used to develop scalable, efficient, and stereoselective manufacturing routes.
Basic Information
| Product Name | Dichloro[(R)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(R)-1,1-Bis(p-Methoxyphenyl)-2-Isopropylethane-1,2-Diamine]Ruthenium(II) |
| CAS No. | 329735-86-6 |
| Molecular Formula | C71H66Cl2N2O2P2Ru |
| Molecular Weight | 1194.10 g/mol |
| Synonyms | (R,R)-RuCl2(BINAP)(DAIPEN); RuCl2[(R)-BINAP][(R)-DAIPEN]; Dichloro[(R)-BINAP][(R)-DAIPEN]ruthenium(II); Noyori-Ikariya Catalyst (Type); (R,R)-Noyori Catalyst; Asymmetric Hydrogenation Catalyst (Ru-BINAP-DPEN Type); Ruthenium(II) (R)-BINAP (R)-DAIPEN Dichloride; (R,R)-[RuCl2(binap)(daipen)] |
| EINECS | Contact for details |
Quality Control
Our Dichloro[(R)-BINAP][(R)-DAIPEN]ruthenium(II) is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated place, separate from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red-brown crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Chiral Purity | ≥ 99.0% ee |
| Residual Solvents (GC) | Meets ICH guidelines |
| Moisture (KF) | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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