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Dichloro[(R)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(R)-1,1-Bis(p-Methoxyphenyl)-2-Isopropylethane-1,2-Diamine]Ruthenium(Ii) CAS NO 329735-86-6


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CAS No.:329735-86-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dichloro[(R)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(R)-1,1-Bis(p-Methoxyphenyl)-2-Isopropylethane-1,2-Diamine]Ruthenium(II) is a highly sophisticated, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a premier catalyst for enantioselective hydrogenation and transfer hydrogenation reactions, enabling the production of single-isomer intermediates with high optical purity. It is critically needed by R&D and production chemists in the pharmaceutical and fine chemical industries for synthesizing chiral active pharmaceutical ingredients (APIs) and advanced materials.

Application

  • Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of ketones, imines, and functionalized olefins to produce chiral alcohols and amines.
  • Pharmaceutical Intermediate Synthesis: Key catalyst in the production of chiral building blocks for APIs, including β-amino acids and derivatives.
  • Transfer Hydrogenation: Employed in reactions using hydrogen donors like isopropanol or formic acid for selective reductions under mild conditions.
  • Fine Chemical Manufacturing: Enables the synthesis of high-value, enantiomerically pure compounds for agrochemicals, flavors, and fragrances.
  • Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
  • Process Chemistry Optimization: Used to develop scalable, efficient, and stereoselective manufacturing routes.

Basic Information

Product Name Dichloro[(R)-2,2'-Bis(Diphenylphosphino)-1,1'-Binaphthyl][(R)-1,1-Bis(p-Methoxyphenyl)-2-Isopropylethane-1,2-Diamine]Ruthenium(II)
CAS No. 329735-86-6
Molecular Formula C71H66Cl2N2O2P2Ru
Molecular Weight 1194.10 g/mol
Synonyms (R,R)-RuCl2(BINAP)(DAIPEN); RuCl2[(R)-BINAP][(R)-DAIPEN]; Dichloro[(R)-BINAP][(R)-DAIPEN]ruthenium(II); Noyori-Ikariya Catalyst (Type); (R,R)-Noyori Catalyst; Asymmetric Hydrogenation Catalyst (Ru-BINAP-DPEN Type); Ruthenium(II) (R)-BINAP (R)-DAIPEN Dichloride; (R,R)-[RuCl2(binap)(daipen)]
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Quality Control

Our Dichloro[(R)-BINAP][(R)-DAIPEN]ruthenium(II) is manufactured under controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and residual solvent content is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated place, separate from incompatible materials.

Specification

Item Specification
Appearance Orange to red-brown crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Chiral Purity ≥ 99.0% ee
Residual Solvents (GC) Meets ICH guidelines
Moisture (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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