Description

1-(4-Bromobenzoyl)-4-Methylpiperidine is a high-purity, specialized organic intermediate featuring a brominated benzoyl moiety linked to a methylpiperidine scaffold. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of potential drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bromine atom for further functionalization.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital component for custom chemical synthesis houses serving the life sciences industry.
• Academic and Institutional Research: Used in university and government laboratories for fundamental organic chemistry and medicinal chemistry studies.

Basic Information

Product Name	1-(4-Bromobenzoyl)-4-Methylpiperidine
CAS No.	329713-82-8
Molecular Formula	C13H16BrNO
Molecular Weight	282.18 g/mol
Synonyms	4'-Bromo-4-methylpiperidin-1-yl phenylmethanone; 1-(4-Bromobenzoyl)-4-methylpiperidine; 4-Methyl-1-(4-bromobenzoyl)piperidine; 4-Bromophenyl 4-methylpiperidin-1-yl ketone; (4-Bromophenyl)(4-methylpiperidin-1-yl)methanone; 4-Methylpiperidine-1-(4-bromobenzoyl); 329713-82-8 (CAS)
EINECS	Contact for details

Quality Control

Our 1-(4-Bromobenzoyl)-4-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.