Description

(1R, 4R, 5S)-4-Hydroxymethyl-Cyclohex-2-En-1,5-Diol is a high-purity, chiral cyclohexene derivative with significant synthetic utility. This compound serves as a valuable advanced pharmaceutical intermediate (API) and a versatile chiral building block for complex organic synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise stereochemistry is critical for biological activity and material properties.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anti-inflammatory, or neurological drugs.
• Chiral Building Block: Used in asymmetric synthesis to construct complex natural products and bioactive molecules with defined stereocenters.
• Agrochemical Synthesis: Intermediate for developing novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a starting material for specialty chemicals, flavors, fragrances, and advanced materials requiring specific three-dimensional architecture.
• Academic & R&D: A critical reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of enantiomerically pure compounds.

Basic Information

Product Name	(1R, 4R, 5S)-4-Hydroxymethyl-Cyclohex-2-En-1,5-Diol
CAS No.	328926-81-4
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(1R,4R,5S)-4-(Hydroxymethyl)cyclohex-2-ene-1,5-diol; (1R,4R,5S)-4-Hydroxymethyl-2-cyclohexene-1,5-diol; (1R,4R,5S)-4-(Hydroxymethyl)-2-cyclohexene-1,5-diol; (1R,4R,5S)-1,5-Dihydroxy-4-(hydroxymethyl)cyclohex-2-ene; 4-Hydroxymethyl-Cyclohex-2-En-1,5-Diol (specifying (1R,4R,5S) isomer); Chiral Cyclohexene Triol Derivative
EINECS	Contact for details

Quality Control

Every batch of (1R, 4R, 5S)-4-Hydroxymethyl-Cyclohex-2-En-1,5-Diol is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided to guarantee compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.