Description

1-(Bromomethyl)-3-[(2-Methylpropan-2-Yl)Oxy]Benzene is a specialized aromatic ether and benzyl bromide derivative, serving as a versatile and high-value synthetic intermediate in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a protecting tert-butoxy group, makes it a critical building block for constructing complex molecules with precise regiochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require reliable, high-purity intermediates for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected phenolic functionality.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the benzyl bromide moiety enables further functionalization.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of novel monomers, polymers, and dendritic structures with specific ether linkages.
• Chemical Biology Probes: Useful for the site-specific modification of biomolecules and the preparation of molecular probes for biochemical assays.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	1-(Bromomethyl)-3-[(2-Methylpropan-2-Yl)Oxy]Benzene
CAS No.	327184-93-0
Molecular Formula	C12H17BrO
Molecular Weight	257.17 g/mol
Synonyms	3-(tert-Butoxy)benzyl Bromide; 1-(Bromomethyl)-3-(tert-butoxy)benzene; 3-(tert-Butyloxy)benzyl Bromide; m-(tert-Butoxy)benzyl Bromide; 3-tert-Butoxybenzyl Bromide; (3-(tert-Butoxy)phenyl)methyl Bromide; Benzene, 1-(bromomethyl)-3-[(2-methyl-2-propanyl)oxy]-; 327184-93-0
EINECS	Contact for details

Quality Control

Our production of 1-(Bromomethyl)-3-[(2-Methylpropan-2-Yl)Oxy]Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all critical quality attributes are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.