Description

4-Bromo-1-Methyl-1H-Pyrazole-5-Carbonitrile is a versatile and high-value brominated pyrazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its reactive bromine and nitrile functional groups, which enable efficient, site-specific derivatization for constructing complex heterocyclic scaffolds. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing new active ingredients, particularly for applications requiring a substituted pyrazole core.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly kinase inhibitors, antiviral agents, and other biologically active small molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate a halogenated pyrazole moiety.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating chemical probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Product Name	4-Bromo-1-Methyl-1H-Pyrazole-5-Carbonitrile
CAS No.	327099-80-9
Molecular Formula	C5H4BrN3
Molecular Weight	185.01 g/mol
Synonyms	4-Bromo-1-methyl-1H-pyrazole-5-carbonitrile; 4-Bromo-1-methylpyrazole-5-carbonitrile; 1-Methyl-4-bromo-1H-pyrazole-5-carbonitrile; 5-Cyano-4-bromo-1-methylpyrazole; 4-Bromo-1-methyl-5-cyanopyrazole; 327099-80-9; 4-Bromo-1-methylpyrazole-5-nitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methyl-1H-Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.